Thermo Fisher Scientific CATSPER4 Polyclonal Antibody
Human CATSPER4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. 정자 기능 연구 등 생식 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CATSPER4. Recombinant protein control fragment (Product # RP-99995) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639319 |
Product Specific Information
Immunogen sequence:
GQQQRITFSE TGAEEEEEND QLPLVHCVVA RSEKSGLLQE PLAGGPLSNL SENTCDNFCL VLEAIQENLR QYKEIRD
- Highest antigen sequence identity to orthologs:
- Mouse: 62%
- Rat: 71%
Target Information
CatSper4 is a protein encoded by the CATSPER4 gene in humans.
It belongs to the cation channels of sperm family, forming a Ca²⁺-permeant ion channel essential for sperm cell function.
This voltage-gated calcium channel plays a crucial role in calcium-dependent physiological responses required for successful fertilization, including:
- Sperm hyperactivation
- Acrosome reaction
- Chemotaxis toward the oocyte
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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