Thermo Fisher Scientific MRPL12 Polyclonal Antibody
Rat MRPL12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, Affinity chromatography로 정제되었습니다. PBS와 2% sucrose buffer에 보관되며 -20°C에서 보존합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of rat MRPL12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690320 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
Target Information
MRPL12 (mitochondrial ribosomal protein L12), also known as 5c5-2, L12mt, MRPL7, or RPML12, is a mammalian mitochondrial ribosomal protein involved in protein synthesis within the mitochondrion. It is enhanced in growth-stimulated cells due to transcriptional activation, suggesting a role as a translational regulator of mitochondrial mRNAs.
Impairment of MRPL12 leads to reduced cell growth rate, decreased mitochondrial ATP production, and loss of oxidative phosphorylation. MRPL12 exists as dimers binding to the large ribosomal subunit, is 198 amino acids long, belongs to the ribosomal protein L12P family, and is highly expressed in the colon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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