
Thermo Fisher Scientific Phospho-BLNK (Tyr189) Polyclonal Antibody
BLNK 단백질의 Tyr189 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 분석에 적합. Protein A로 정제된 고순도 항체로, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human BLNK around Tyr189 [EN(p-Y)IH] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
B cell linker protein (BLNK), also known as SLP-65, is an adaptor protein encoded by the BLNK gene on chromosome 10 in humans. It plays a critical role in B cell receptor (BCR) signaling. BLNK is phosphorylated by Syk kinase upon BCR activation, providing a scaffold for downstream signaling molecules such as Vav GEF and Grb2. Deficiency of BLNK leads to impaired B cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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