Thermo Fisher Scientific E6AP Polyclonal Antibody
E6AP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 UBE3A(400–450aa) 영역을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A300352Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific E6AP Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1–4 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 and 450 of human Ubiquitin Protein Ligase E3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
UBE3A (ubiquitin-protein ligase E3A, also known as E6AP) is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 conjugating enzyme to its substrates. Identified substrates include ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, PML tumor suppressor, and CDKN1B. UBE3A also assists in degradation of misfolded cytoplasmic proteins and plays a role in circadian rhythm regulation. Defects in UBE3A are associated with Angelman syndrome (AS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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