
Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI4C2), TrueMAB
BTLA 단백질을 인식하는 Mouse monoclonal 항체로, Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. Lyophilized 형태로 공급되며, 재구성 후 1 mg/mL 농도 사용 가능. 연구용으로 면역조절 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C2 |
| Immunogen | Full length human recombinant protein of human BTLA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure the antibody is carrier-free.
Target Information
BTLA (B and T-lymphocyte attenuator) is a member of the co-inhibitory receptors of the CD28 superfamily.
It functions as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activity.
BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon T cell activation.
It remains expressed on Th1 cells but not Th2 cells and interacts with the TNFR superfamily member HVEM, playing a key role in lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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