Thermo Fisher Scientific MFN2 Monoclonal Antibody (6A8)
MFN2 단클론 항체(6A8)는 인간, 마우스, 랫트에 반응하며 Western blot, IHC, ELISA 등에 사용 가능. 미토콘드리아 융합 관련 단백질을 표적화하며, 고순도 친화성 크로마토그래피로 정제된 액상 항체. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6A8 |
| Immunogen | MFN2 (NP_055689, 661–757 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FKRQFVEHAS EKLQLVISYT GSNCSHQVQQ ELSGTFAHLC QQVDVTRENL EQEIAAMNKK IEVLDSLQSK AKLLRNKAGW LDSELNMFTH QYLQPSR
Target Information
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in regulation of vascular smooth muscle cell proliferation and may play a role in obesity pathophysiology. Mutations in MFN2 cause Charcot-Marie-Tooth disease type 2A2 and hereditary motor and sensory neuropathy VI, both peripheral nervous system disorders. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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