Thermo Fisher Scientific Phospho-DAXX (Ser668) Polyclonal Antibody
Phospho-DAXX (Ser668) 폴리클로날 항체로 인간 및 마우스 시료에 반응. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. KLH 결합 합성 인산화 펩타이드로 면역원 제작. 고순도 Protein A 정제, 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser668 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and cytoplasm. It interacts with various proteins such as apoptosis antigen Fas, centromere protein C, and transcription factor E26 oncogene homolog 1. In the nucleus, it functions as a transcription repressor binding to sumoylated transcription factors, and repression can be relieved by sequestration into promyelocytic leukemia nuclear bodies or nucleoli. It also associates with centromeres during G2 phase. In the cytoplasm, it may regulate apoptosis. Subcellular localization and function are modulated by post-translational modifications including sumoylation, phosphorylation, and polyubiquitination. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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