Thermo Fisher Scientific MRPL52 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRPL52 protein. Validated for IHC(P) and ICC/IF applications. Supplied unconjugated in liquid form at 1 mg/mL concentration. Ideal for mitochondrial ribosomal protein research. For research use only.
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Thermo Fisher Scientific MRPL52 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human MRPL52 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555561 |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within mitochondria. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising mitoribosomes vary greatly among species, making sequence homology recognition difficult. The MRPL52 gene encodes a 39S subunit protein with no bacterial homolog, and multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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