Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI1C10), TrueMAB
인간 BAIAP2 단백질을 인식하는 마우스 단클론 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. 고순도 Affinity chromatography 정제, 액상 형태(1 mg/mL), 안정적인 PBS/BSA/glycerol buffer 구성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C10 |
| Immunogen | Full length human recombinant protein of BAIAP2 produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It associates with a downstream effector of Rho small G proteins, involved in stress fiber formation and cytokinesis. This protein plays a role in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. It also interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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