Thermo Fisher Scientific 2-hydroxyisobutyryl-Histone H1.2 (Lys116) Polyclonal Antibody
2-hydroxyisobutyryl-Histone H1.2 (Lys116)에 특이적인 Rabbit Polyclonal Antibody로 인간 시료에 반응. ICC/IF, ELISA, ChIP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. PBS 및 50% glycerol buffer에 보관하며 -20°C 이하에서 안정적.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:20–1:200 | - |
| ELISA | Assay-dependent | - |
| ChIP assay | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of 2-hydroxyisobutyryl-Lys (116) derived from Human Histone H1.2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.24 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091421 |
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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