Thermo Fisher Scientific Active/Pro-Caspase 3 Recombinant Rabbit Monoclonal Antibody (23GB720)
Active/Pro-Caspase 3 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot에 최적화되어 있으며 인간, 마우스, 랫트 반응성. 액상 형태로 제공되며 PBS/glycerol buffer에 보존. 세포사멸 관련 연구용으로 적합.
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Thermo Fisher Scientific Active/Pro-Caspase 3 Recombinant Rabbit Monoclonal Antibody (23GB720)
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB720 |
| Immunogen | A synthetic peptide of human active + pro Caspase 3 (1–175AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, which dimerize to form the active enzyme.
This protein cleaves and activates caspases 6, 7, and 9, and is itself processed by caspases 8, 9, and 10. It is the predominant caspase involved in cleavage of amyloid-beta 4A precursor protein, associated with neuronal death in Alzheimer’s disease. Alternative splicing of this gene results in two transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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