Thermo Fisher Scientific WDR48 Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:500

Product Specifications

Target Information

WD-repeats are motifs found in various proteins characterized by a conserved core of 40–60 amino acids forming a tertiary propeller structure. Proteins containing WD-repeats participate in cellular functions such as signal transduction, apoptosis, transcriptional regulation, and cell cycle control. WD repeats mediate protein-protein interactions and assembly of protein complexes.
WDR48 (WD repeat-containing protein 48), also known as USP1-associated factor 1 and p80, is a 677 amino acid protein regulating deubiquitinating complexes via activation of USP1, USP12, and USP46. It enhances deubiquitination by increasing catalytic turnover without altering substrate affinity. WDR48 is ubiquitously expressed, mainly localized in the cytoplasm, and has five isoforms produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.