Thermo Fisher Scientific MAGI2 Monoclonal Antibody (6F5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

6F5

Immunogen

MAGI2 (NP_036433, 519 a.a. approximately 628 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGI2,uniProtId:Q86UL8-1,ncbiNodeId:9606,antigenRange:519-628,antigenLength:1455,antigenImageFileName:H00009863-M02_MAGI2_Q86UL8-1_House_mouse.svg,antigenImageFileNamePDP:H00009863-M02_MAGI2_Q86UL8-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PANSMVPPLA IMERPPPVMV NGRHNYETYL EYISRTSQSV PDITDRPPHS LHSMPTDGQL DGTYPPPVHD DNVSMASSGA TQAELMTLTI VKGAQGFGFT IADSPTGQRV

Target Information

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.