Thermo Fisher Scientific Human HHATL Synthetic Peptide
인간 HHATL 단백질의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드. 폴리클로날 항체 PA5-34355의 블로킹 펩타이드로 사용 가능. Hedgehog 신호 경로 연구 및 단백질 상호작용 분석에 적합. 고순도 정제, 액상 형태, -20°C 보관.
- 카탈로그번호
- PEP1398
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human HHATL.
PEP-1398 can be used as a blocking peptide with polyclonal antibody PA5-34355.
Target Information
HHATL (Hedgehog Acyltransferase-Like) is a gene that codes for a protein involved in the regulation of Hedgehog signaling pathways. HHATL is located on chromosome 7q36.3. Structurally, the protein encoded by this gene is characterized by an acyltransferase domain, which plays a crucial role in the N-palmitoylation of the Sonic Hedgehog (Shh) protein, a process essential for its proper signaling activity and distribution. Functionally, HHATL has been implicated in various biological processes, including amelioration of endoplasmic reticulum stress through autophagy. The gene is expressed in several tissues, with notable high expression in the heart, suggesting a potential role in cardiac development and function. Dysfunction in HHATL could lead to anomalies in Hedgehog signaling, impacting various developmental and cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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