
Thermo Fisher Scientific Angiotensinogen Monoclonal Antibody (03)
인간 Angiotensinogen/SerpinA8에 특이적인 단클론 항체로 ELISA에 적합합니다. 보존제가 포함되지 않은 액상 형태이며 Protein A로 정제되었습니다. 단기 보관은 4°C, 장기 보관은 -20°C에서 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
- ELISA (ELISA): 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 03 |
| Immunogen | Recombinant Human Angiotensinogen/SerpinA8 Protein (Met1–Ala485) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785840 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human Angiotensinogen/SerpinA8.
Target Information
The protein encoded by AGT (angiotensinogen precursor) is expressed in the liver and cleaved by renin in response to lowered blood pressure. The resulting angiotensin I is further cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active angiotensin II.
This protein plays a key role in maintaining blood pressure and is involved in essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, renal tubular dysgenesis, non-familial structural atrial fibrillation, and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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