Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI4E5)
QPRT 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4E5). Western blot, ICC/IF, Flow cytometry에 적합. Human 시료 반응성. Affinity Chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E5 |
| Immunogen | Full length human recombinant QPRT protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723540 |
Target Information
The QPRT gene encodes a key enzyme involved in the catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway. Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevated quinolinate levels in the brain have been associated with neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease. Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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