Thermo Fisher Scientific KCNN2 Polyclonal Antibody
KCNN2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal antibody입니다. Western blot과 IHC(P)에서 사용 가능하며, 인간에 반응하고 다른 종에서도 예측 반응성을 보입니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (ESYDKHVTYNAER) corresponding to the internal amino acids of KCNN2 (aa 545–558) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11000612 |
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and mediated by different calcium-activated potassium channels.
The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.
The encoded protein forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene belongs to the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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