
Thermo Fisher Scientific DKK2 Polyclonal Antibody
DKK2 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 시료에 반응합니다. 면역세포염색(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼(40% 글리세롤) 기반의 액상 형태로 4°C 또는 -20°C에서 보관합니다.
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Applications
- Immunocytochemistry (ICC/IF)
Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DKK2. Recombinant protein control fragment (Product #RP-106401) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856767 |
Product Specific Information
Immunogen sequence:
MCCPSTRCNN GICIPVTESI LTPHIPALDG TRHRDRNHGH YSNHDLGWQN LGRPHTKMSH IKGHEGDPCL RSSDCIEGFC C
Target Information
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine-rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/β-catenin signaling, depending on the cellular context and the presence of the co-factor Kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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