Thermo Fisher Scientific PKP1 Polyclonal Antibody
PKP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC(P), ICC/IF에 적합합니다. Human 및 Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 세포 간 결합 및 데스모좀 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PKP1 (Recombinant protein control fragment: Product #RP-94030) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790114 |
Product Specific Information
Immunogen sequence:
YTVRNLMASQ PQLAKQYFSS SMLNNIINLC RSSASPKAAE AARLLLSDMW SSKELQGVLR QQGFDRNMLG TLAGANSLRN FTSRF
Target Information
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families.
Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton.
This protein may be involved in molecular recruitment and stabilization during desmosome formation.
Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome.
Two transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Jul 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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