Thermo Fisher Scientific EHMT1 Monoclonal Antibody (3G1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3G1

Immunogen

EHMT1 (NP_079033, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EHMT1,uniProtId:Q9H9B1-1,ncbiNodeId:9606,antigenRange:1-100,antigenLength:1298,antigenImageFileName:H00079813-M05_EHMT1_Q9H9B1-1_House_mouse.svg,antigenImageFileNamePDP:H00079813-M05_EHMT1_Q9H9B1-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAADEGSAEK QAGEAHMAAD GETNGSCENS DASSHANAAK HTQDSARVNP QDGTNTLTRI AENGVSERDS EAAKQNHVTA DDFVQTSVIG SNGYILNKPA

Target Information

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates Lys-9 of histone H3 in vitro. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.