Thermo Fisher Scientific EHMT1 Monoclonal Antibody (3G1)
EHMT1 단백질을 인식하는 Thermo Fisher Scientific의 Monoclonal Antibody (Clone 3G1). Western blot, ICC/IF, ELISA에 적합하며, Human 시료에 반응. PBS buffer 기반 액상형, 무보존제, -20°C 보관.
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- H00079813-M05
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G1 |
| Immunogen | EHMT1 (NP_079033, 1–100 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAADEGSAEK QAGEAHMAAD GETNGSCENS DASSHANAAK HTQDSARVNP QDGTNTLTRI AENGVSERDS EAAKQNHVTA DDFVQTSVIG SNGYILNKPA
Target Information
EHMT1, also known as EUHMTASE1, is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro.
H3 Lys-9 methylation acts as a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones.
EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and/or DP1.
During the G0 phase, it may contribute to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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