
Thermo Fisher Scientific Gemin 1/SMA Polyclonal Antibody
Gemin 1/SMA 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 액상 형태이며, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Gemin 1/SMA Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Gemin 1 (amino acids 31–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This region includes multiple genes and repetitive elements, making it prone to rearrangements and deletions. The telomeric and centromeric copies encode the same survival motor neuron protein. The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins, essential components of the spliceosome. Mutations in SMN1 are associated with spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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