Thermo Fisher Scientific PPP1R8 Polyclonal Antibody
PPP1R8 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합하며 사람, 마우스, 랫트 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 안정적 보관 가능.
- 카탈로그번호
- PA555601
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP1R8. Recombinant protein control fragment (Product #RP-94133). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645880 |
Product Specific Information
Immunogen sequence:
ISTLTIEEGN LDIQRPKRKR KNSRVTFSED DEIINPEDVD PSVGRFRNMV QTAVVPVKKK RVEGPGSLGL EESGSRRMQN FAFSGGLY
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 97%
Target Information
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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