Thermo Fisher Scientific IDH1 Recombinant Rabbit Monoclonal Antibody (23GB2105)
IDH1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot과 유세포분석(Flow cytometry)에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, HEK293F 시스템에서 발현되었습니다. 고순도의 친화 크로마토그래피 정제 제품으로 연구용에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2105 |
| Immunogen | A synthesized peptide derived from human IDH1 (1–70AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses: one utilizing NAD(+) and the other NADP(+) as electron acceptors.
Five isocitrate dehydrogenases have been reported — three NAD(+)-dependent (mitochondrial) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
The IDH1 gene encodes the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains a PTS-1 peroxisomal targeting signal sequence and plays a role in regenerating NADPH for intraperoxisomal reductions and cytoplasmic NADPH production.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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