Thermo Fisher Scientific PADI4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:20-1:50

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 290-663 of human PADI4 (NP_0365192) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PADI4,uniProtId:Q9UM07-1,ncbiNodeId:9606,antigenRange:290-663,antigenLength:663,antigenImageFileName:PA5-110070_PADI4_Q9UM07-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110070_PADI4_Q9UM07-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.08 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855481

Product Specific Information

Immunogen sequence: VFRVAPWIMT PNTQPPQEVY ACSIFENEDF LKSVTTLAMK AKCKLTICPE EENMDDQWMQ DEMEIGYIQA PHKTLPVVFD SPRNRGLKEF PIKRVMGPDF GYVTRGPQTG GISGLDSFGN LEVSPPVTVR GKEYPLGRIL FGDSCYPSND SRQMHQALQD FLSAQQVQAP VKLYSDWLSV GHVDEFLSFV PAPDRKGFRL LLASPRSCYK LFQEQQNEGH GEALLFEGIK KKKQQKIKNI LSNKTLREHN SFVERCIDWN RELLKRELGL AESDIIDIPQ LFKLKEFSKA EAFFPNMVNM LVLGKHLGIP KPFGPVINGR CCLEEKVCSL LEPLGLQCTF INDFFTYHIR HGEVHCGTNV RRKPFSFKWW NMVP

Target Information

Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at Arg-8 and/or Arg-17 and histone H4 at Arg-3, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at Arg-2142, which favors its interaction with NCOA2/GRIP1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.