Thermo Fisher Scientific CD200 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD200. Recognizes recombinant CD200 protein. Supplied as liquid form at 0.1 mg/mL. Suitable for research use in studying macrophage regulation and CD200/CD200R interactions. Store at 4°C short term or -20°C lo...
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CD200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790338 |
Product Specific Information
Immunogen sequence:
EREQLYTPAS LKCSLQNAQE ALIVTWQKKK AVSPENMVTF SENHGVVIQP AYKDKINITQ LGLQNSTITF WNITLEDEGC YMCLFNTFGF GKISGTACLT VYVQPIVSLH YKFSEDHLNI TCSATARPAP MVFWKVPRS
Target Information
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains and belongs to the immunoglobulin superfamily. It is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation.
Homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies in mouse and rat suggest that CD200 may regulate myeloid cell activity and deliver inhibitory signals for macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants encoding different isoforms of CD200 have been identified.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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