Thermo Fisher Scientific UBP1 Polyclonal Antibody
UBP1 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. 인간 및 생쥐 시료에 반응하며, IHC(P) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고농도(2.7 mg/mL) 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific UBP1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human upstream binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636148 |
Product Specific Information
The antibody detects endogenous levels of total UBP1 protein.
Target Information
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. It modulates placental expression of CYP11A1 and regulates the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter occurs via synergistic interaction with TFCP2. UBP1 binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box, repressing HIV-1 transcription by inhibiting TFIID binding to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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