Thermo Fisher Scientific Neurogenin 1 Polyclonal Antibody
Neurogenin 1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도의 Affinity Chromatography로 정제되었습니다. 신경발생 연구 및 세포 분화 조절 메커니즘 분석에 유용합니다.
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- PA540478
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human NEUROG1 (aa 180–229) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606240 |
Product Specific Information
Peptide sequence:
ASDAESWGSG AAAASPLSDP SSPAASEDFT YRPGDPVFSF PSLPKDLLHT
Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 93%
Human: 100%
Mouse: 93%
Pig: 100%
Rabbit: 79%
Rat: 93%
Target Information
Neurogenin 1 (NeuroG1) is a basic helix-loop-helix (bHLH) transcription factor involved in determining cell type during development. It plays dual roles in cell-fate specification — promoting neurogenesis as a transcriptional activator and inhibiting astrocyte differentiation. NeuroG1 achieves this by sequestering the CREB-binding protein transcription complex away from astrocyte differentiation genes and inhibiting STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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