Thermo Fisher Scientific ITGA3 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1303)

Applications

• ELISA (ELISA): Assay-dependent

Product Specifications

Product Specific Information

• Compatible with Direct ELISA

Target Information

ITGA3 (INTEGRIN, ALPHA-3), also known as CD49C, VLA3, or GAPB3, is a protein encoded by the ITGA3 gene in humans. It belongs to the family of cell surface adhesion molecules and is mapped to chromosome 17q21.33.
The ITGA3 subunit forms part of the alpha3beta1 integrin complex, which plays a critical role in neural migration and corticogenesis in association with the beta-1 subunit.
A functional link between DAB1 phosphorylation and ITGA3 signaling regulates the detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 has been shown to increase viral infectivity in Chinese hamster ovary cells.
ITGA3 contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and 7 N-terminal repeating units characteristic of integrins. Recombinant ITGA3 is expressed as a 150-kD protein, consistent with the native protein as confirmed by western blot analysis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.