Thermo Fisher Scientific TFPI Recombinant Rabbit Monoclonal Antibody (3)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select the best clones for production.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

This antibody has specificity for Human TFPI/LACI/EPI.

Target Information

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.

The coagulation process initiates with the formation of a factor VIIa–TF complex, which activates additional proteases (factors IX and X) and leads to fibrin clot formation. TFPI inhibits activated factor X and VIIa–TF proteases in an autoregulatory loop.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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