Thermo Fisher Scientific KCNH2 Polyclonal Antibody
KCNH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에 반응하며 IHC(P) 등 연구용으로 적합. 항원 친화 크로마토그래피로 정제된 액상 형태로, 장기 보관 시 -20°C에서 안정적 유지.
- 카탈로그번호
- PA533867
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human KCNH2 / Kv11.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551236 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Pig (100%).
Target Information
Human ether-a-go-go related gene (HERG) encodes the pore-forming alpha subunit of the delayed rectifier potassium channel IKr.
There are two N-terminal splice variants of HERG: isoform 1 alpha (full-length) and isoform 1 beta (shorter).
Isoform 1 beta lacks the PAS motif and deactivates faster than isoform 1 alpha.
Residues within the C-terminal region play a role in channel expression and gating, including voltage-dependent activation.
HERG is expressed in cardiac tissue, predominantly in ventricles.
Mutations in HERG are associated with long QT syndrome type 2 and short QT syndrome type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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