Thermo Fisher Scientific ZDHHC18 Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal ZDHHC18 항체로 Western Blot, IHC, ELISA에 적합. 고순도 Affinity chromatography로 정제된 액상 형태이며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 301–388 of human ZDHHC18 (NP_1156591) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.99 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901245 |
Product Specific Information
- Positive Samples: Raji, HeLa, Mouse brain, Rat brain
- Immunogen sequence:
YLVASNLTTN EDIKGSWSSK RGGEASVNPY SHKSIITNCC AVLCGPLPPS LIDRRGFVQS DTVLPSPIRS DEPACRAKPD ASMVGGHP
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, often involving transcriptional activation or repression.
ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 or C16orf1, is a 485 amino acid multi-pass membrane protein with one DHHC-type zinc finger.
It is expressed in fetal heart, lung, and kidney, and also in adult lung and pancreas.
ZDHHC1 functions as a palmitoyltransferase catalyzing conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA.
Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7, and ZDHHC18 each contain one DHHC-type zinc finger and exhibit palmitoyltransferase activity against substrates such as H-Ras, SNAP25, and GABAA R proteins.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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