Thermo Fisher Scientific YAF2 Polyclonal Antibody
YAF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. 인간에 반응하며, Protein A로 정제된 액상 형태입니다. PBS + sucrose buffer에 보관하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific YAF2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1.25 µg/mL
- Immunohistochemistry (IHC): 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human YAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606806 |
Product Specific Information
- Peptide sequence: KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK
- Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Target Information
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium-activated protease m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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