Thermo Fisher Scientific NFYC Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (IHC)

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human(unreviewed) hCBF-C(Accession Q14497), corresponding to amino acid residues T10-R25. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NFYC,uniProtId:Q13952-1,ncbiNodeId:9606,antigenRange:10-25,antigenLength:458,antigenImageFileName:PA5-106455_NFYC_Q13952-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106455_NFYC_Q13952-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817655

Product Specific Information

Antibody detects endogenous levels of total CBF-C.

Target Information

The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold handshake motif in a manner analogous to the histone proteins, H2B and H2A, respectively.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.