Thermo Fisher Scientific Connexin 40 Polyclonal Antibody
Connexin 40 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC(Paraffin) 실험에 사용 가능하며, Mouse 반응성을 보입니다. 동결건조 형태로 제공되며, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse Connexin-40 conjugated to a blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide shares 95% identity with rat sequence.
- Specificity of this antibody: Connexin-40.
Target Information
Connexin 40 (Cx40) belongs to the connexin family of gap junction proteins, which are expressed in pancreas, kidney, skeletal muscle, liver, placenta, and heart.
Cx40 is highly expressed in vascular endothelial cells and the mammalian heart, specifically in the atrial myocardium and the His-Purkinje conduction system.
At least three other connexins are expressed in the heart, including:
- Cx37 (endocardium)
- Cx43 (atrial and ventricular myocardium, distal parts of the conduction system)
- Cx45 (throughout the heart)
Cx40 and Cx43 frequently co-localize in cardiovascular cells and participate in forming heterotypic gap junction channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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