Thermo Fisher Scientific Cathepsin C Polyclonal Antibody
Thermo Fisher Scientific의 Cathepsin C Polyclonal Antibody는 인간 Cathepsin C 단백질을 인식하는 염소 유래 IgG 항체입니다. Western blot 및 IHC(P) 응용에 적합하며, 고순도 및 안정적 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RNVHGINFVSPVRNQ, from the internal region of CTSC (aa238–252) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554457 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
Cathepsin C, also known as dipeptidyl aminopeptidase I (DPPI), is a tetrameric lysosomal cysteine peptidase belonging to the papain family. It is involved in intracellular protein degradation and processing of protein precursors, participating in cell growth, neuraminidase activation, and platelet factor XIII activation. Cathepsin C is related to other lysosomal cysteine proteinases such as cathepsin B, H, and L. It sequentially removes dipeptides from the amino terminus and requires chloride ions and thiols for full enzymatic activity. Cathepsin C is expressed in various tissues, most abundantly in spleen, kidney, cytotoxic lymphocytes, and myeloid cells, where it localizes to secretory granules. It is synthesized as a proenzyme that is processed into two chains forming the mature enzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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