Thermo Fisher Scientific INSR Monoclonal Antibody (18-44)
인슐린 수용체(INSR)를 인식하는 마우스 단클론 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 시료에 반응하며, 보존제가 없는 PBS 용액 형태로 제공됩니다. Protein G로 정제되어 안정적인 신호 검출이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–10 µg/mL
- Publications: View 2 publications
ELISA
- Tested Dilution: —
- Publications: View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: 1–10 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 18-44 |
| Immunogen | Human placental insulin receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075408 |
Product Specific Information
- MA1-10865 detects Insulin Receptor from human samples.
- Low cross-reactivity with bovine and rabbit samples.
- Suitable for Western blot and immunoprecipitation applications.
- Immunogen: human placental insulin receptor.
Target Information
INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR.
In humans, the INSR gene is located on chromosome 19. Defects in INSR are associated with various insulin resistance syndromes, while IGF-1R defects may cause growth retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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