Thermo Fisher Scientific Granzyme K Polyclonal Antibody
Human, Mouse, Rat 반응성의 Granzyme K 단백질 검출용 rabbit polyclonal antibody. Western blot, IHC, ICC 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:100–1:300 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from the internal region of human Granzyme K (aa 61–110) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2636428 |
Product Specific Information
Granzyme K Polyclonal Antibody detects endogenous levels of Granzyme K protein.
Target Information
Granzyme K (GrK) is a trypsin-like serine protease localized in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11–12 near the granzyme A gene. Granzyme K cleaves at basic residues arginine and lysine, and triggers rapid cell death independently of caspase activation. It is primarily expressed in thymus, lung, spleen, and peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-50980_Granzyme_K_P49863-1_Rabbit.svg, PA5-50980_Granzyme_K_P49863-1_Rabbit_PDP.jpeg)
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