Thermo Fisher Scientific Phospho-BID (Ser78) Polyclonal Antibody
Phospho-BID (Ser78) 항체로, 마우스 BID 단백질의 인산화된 Ser78 부위를 특이적으로 인식합니다. Western blot 및 면역침강에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Reference |
|---|---|---|
| Western Blot (WB) | 1:250–1:1,000 | - |
| Immunoprecipitation (IP) | See datasheet | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated Serine 78 and surrounding residues of mouse BH3 interacting domain death agonist (BID) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.50 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It is a member of the BCL-2 family of cell death regulators and acts as a mediator of mitochondrial damage induced by caspase-8 (CASP8). Upon cleavage by CASP8, the COOH-terminal fragment translocates to mitochondria, triggering cytochrome c release and apoptosis. BID serves as a direct molecular link between caspase-8 activation and mitochondrial death machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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