Thermo Fisher Scientific BRP44L Polyclonal Antibody
BRP44L 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 버퍼에 보관. 인간 BRP44L 재조합 단백질로 면역화되어 높은 특이성과 재현성을 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BRP44L (Recombinant protein control fragment: Product #RP-100810) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638597 |
Product Specific Information
Immunogen sequence:
MAGALVRKAA DYVRSKDFRD YLMSTHFWGP VANWGLPIAA INDMKKSPEI ISGR
Highest antigen sequence identity to the following orthologs:
- Mouse – 100%
- Rat – 100%
Target Information
BRP44L (Brain Protein 44-like protein), also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family.
The BRP44L gene maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence (~6% of the human genome).
Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus.
Chromosome 6 is also linked to several genetic conditions including:
- Porphyria cutanea tarda (via HFE gene mutations)
- Parkinson’s disease (via PARK2 gene)
- Rheumatic diseases (via MHC complex)
- Stickler syndrome, 21-hydroxylase deficiency, and maple syrup urine disease
- A bipolar disorder susceptibility locus on the q arm
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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