Thermo Fisher Scientific TRIP13 Polyclonal Antibody
TRIP13 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 4°C 단기 보관, -20°C 장기 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRIP13. Recombinant protein control fragment (Product #RP-89294). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648956 |
Product Specific Information
Immunogen sequence:
STAKKEDINL SVRKLLNRHN IVFGDYTWTE FDEPFLTRNV QSVSIIDTEL KVKDSQPIDL SACTVALHIF QLNEDGPSSE NLEEETENII AANHWVLPAA EFHGLWDSLV YDVEVKSH
Antigen sequence identity:
- Mouse: 88%
- Rat: 89%
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner.
TRIP13 (thyroid hormone receptor interactor 13), also known as 16E1BP, interacts with the ligand binding domain of the thyroid receptor (TR) and various target genes including human papilloma virus type 16 (HPV16) E1.
Unlike most TRIP proteins that function only in the presence of hormones, TRIP13 interacts with TR even in the absence of thyroid hormone.
The association of TRIP13 with HPV16 E1 suggests a potential tumor suppressor gene function. TRIP13 is a 432 amino acid protein with two different isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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