Thermo Fisher Scientific NAM8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Yeast

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Saccharomyces cerevisiae (strain ATCC 204508/S288c) (Bakers yeast) NAM8 protein if (typeof window.$mangular ===undefined|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson =[{targetFamily:NAM8,uniProtId:Q00539-1,ncbiNodeId:-23,antigenRange:1-219,antigenLength:523,antigenImageFileName:PA5-144487\_NAM8\_Q00539-1\_Rabbit.svg,antigenImageFileNamePDP:PA5-144487\_NAM8\_Q00539-1\_Rabbit\_PDP.jpeg,sortOrder:1}]; $mangular.isB2BCMGT = ``false``; $mangular.isEpitopesModalImageMultiSizeEnabled =true`;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.28 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% Proclin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_3091710

Target Information

Component of the U1 small nuclear ribonucleoprotein complex (U1 snRNP) involved in the initiation of meiotic recombination (PubMed:1603056, PubMed:7625279). Involved in the formation of DSBs at recombination hot-spots through meiosis-specific splicing of REC107 pre-mRNA (PubMed:7625279, PubMed:9112441, PubMed:21788335). Collaborates with MER1 to promote splicing of essential meiotic mRNAs REC10, AMA1, MER3, HFM1, SPO22 and PCH2 (PubMed:10983980, PubMed:21208980, PubMed:21788335). NAM8 interacts with the pre-mRNA downstream of the 5` splice site, in a region of non-conserved sequence and is required for efficient splicing of uncapped RNA precursor (PubMed:10072385).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.