Thermo Fisher Scientific CST6 Monoclonal Antibody (2H8)
CST6 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체(2H8). Western blot 및 ELISA에 적합하며, Human 시료 반응성. PBS buffer에 용해된 액상 형태로, 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H8 |
| Immunogen | CST6 (AAH31334, 29–149 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RPQERMVGEL RDLSPDDPQV QKAAQAAVAS YNMGSNSIYY FRDTHIIKAQ SQLVAGIKYF LTMEMGSTDC RKTRVTGDHV DLTTCPLAAG AQQEKLRCDF EVLVVPWQNS SQLLKHNCVQ M
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors.
- Type 1 cystatins (A, B): mainly intracellular
- Type 2 cystatins (C, D, E/M, F, G, S, SN, SA): extracellular
- Type 3 cystatins (kininogens): intravascular proteins
All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes.
Cystatin SA, S, and SN are primarily found in saliva, and also expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against oral cavity proteinases, while Cystatin E/M and F modulate cathepsin inhibition.
Fetuins, part of the cystatin superfamily, influence osteogenesis, bone resorption, and regulation of insulin and hepatocyte growth factor receptors.
High and low molecular weight kininogens inhibit thrombin- and plasmin-induced thrombocyte aggregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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