Thermo Fisher Scientific WWP1 Polyclonal Antibody
WWP1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태. 세포막 및 세포질, 핵 단백질 검출에 적합.
- 카탈로그번호
- PA592368
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–260 of human WWP1 (NP_008944.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806455 |
Product Specific Information
Immunogen sequence:
MATASPRSDT SNNHSGRLQL QVTVSSAKLK RKKNWFGTAI YTEVVVDGEI TKTAKSSSSS NPKWDEQLTV NVTPQTTLEF QVWSHRTLKA DALLGKATID LKQALLIHNR KLERVKEQLK LSLENKNGIA QTGELTVVLD GLVIEQENIT NCSSSPTIEI QENGDALHEN GEPSARTTAR LAVEGTNGID NHVPTSTLVQ NSCCSYVVNG DNTPSSPSQV AARPKNTPAP KPLASEPADD TVNGESSSFA PTDNASVTGT
- Positive Samples: PC-3
- Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein
Target Information
WW domain-containing proteins are found in all eukaryotes and play an important role in regulating cellular functions such as protein degradation, transcription, and RNA splicing.
This gene encodes a protein containing four tandem WW domains and a HECT domain. The protein belongs to a family of NEDD4-like E3 ubiquitin-ligases that regulate key trafficking decisions, including targeting proteins to proteosomes or lysosomes.
Alternative splicing generates at least six transcript variants, though their full-length nature is not fully defined.
[provided by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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