Thermo Fisher Scientific MAPK15 Monoclonal Antibody (168CT10.6.6)
MAPK15 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB 및 ICC/IF에 적합합니다. 인간 시료 반응성이 있으며 Protein G로 정제된 액상 형태입니다. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific MAPK15 Monoclonal Antibody (168CT10.6.6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 168CT10.6.6 |
| Immunogen | MAPK15 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897414 |
Target Information
The ERKs are a subfamily of the MAPKs involved in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase regulated by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and negatively regulates transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner. This suggests a broader role for ERK8 in regulating nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and contributes to RET biological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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