Thermo Fisher Scientific CDC45L Polyclonal Antibody, MaxPab
CDC45L 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 in situ PLA에 적합합니다. 인간 단백질에 반응하며, 친화 크로마토그래피로 정제된 액상 형태입니다. DNA 복제 관련 연구용으로 사용됩니다.
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Thermo Fisher Scientific CDC45L Polyclonal Antibody, MaxPab
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| in situ PLA (PLA) | 1:1200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CDC45L (NP_003495.1, 1–566 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVVNVY NDTQIKLLIK QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVEQTMR RRQRREWEAR RRDILFDYEQ YEYHGTSSAM VMFELAWMLS KDLNDMLWWA IVGLTDQWVQ DKITQMKYVT DVGVLQRHVS RHNHRNEDEE NTLSVDCTRI SFEYDLRLVL YQHWSLHDSL CNTSYTAARF KLWSVHGQKR LQEFLADMGL PLKQVKQKFQ AMDISLKENL REMIEESANK FGMKDMRVQT FSIHFGFKHK FLASDVVFAT MSLMESPEKD GSGTDHFIQA LDSLSRSNLD KLYHGLELAK KQLRATQQTI ASCLCTNLVI SQGPFLYCSL MEGTPDVMLF SRPASLSLLS KHLLKSFVCS TKNRRCKLLP LVMAAPLSME HGTVTVVGIP PETDSSDRKN FFGRAFEKAA ESTSSRMLHN HFDLSVIELK AEDRSKFLDA LISLLS
Target Information
The protein encoded by this gene shows strong similarity to Saccharomyces cerevisiae Cdc45, an essential protein required for initiation of DNA replication.
Cdc45 is part of a conserved multiprotein complex including Cdc6/Cdc18, MCMs, and DNA polymerase, critical for early eukaryotic DNA replication steps.
It interacts with MCM7 and DNA polymerase alpha and plays a key role in loading DNA polymerase alpha onto chromatin.
Multiple polyadenylation sites are reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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