Thermo Fisher Scientific PMM2 Polyclonal Antibody
PMM2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 저장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PMM2 (Accession O15305), corresponding to amino acid residues D188–R238 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815703 |
Product Specific Information
Antibody detects endogenous levels of total PMM2.
Target Information
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene cause defects in glycoprotein biosynthesis, manifesting as carbohydrate-deficient glycoprotein syndrome type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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