Thermo Fisher Scientific GADD45A Monoclonal Antibody (OTI1C9), TrueMAB
Human GADD45A 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. -20°C 보관, PBS/BSA/glycerol buffer 포뮬레이션. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C9 |
| Immunogen | Full length human recombinant protein of human GADD45A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
GADD45 alpha, beta, and gamma are evolutionarily conserved, homologous nuclear proteins that function as stress sensors for cellular physiological and environmental damage.
GADD45 proteins are required for activation of the G2/M checkpoint induced by UV radiation or alkylating agents.
The GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase.
GADD45 forms a complex with p21 and Cdc2, and may serve as a core for interaction with other cell cycle regulators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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