Thermo Fisher Scientific CCDC53 Polyclonal Antibody
Human CCDC53 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. WASH 복합체 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CCDC53. Recombinant protein control fragment (Product #RP-97726). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639464 |
Product Specific Information
Immunogen sequence:
LMGSGIDLTK VPAIQQKRTV AFLNQFVVHT VQFLNRFSTV CEEKLADLSL RIQQIETTLN ILDAKLSSIP GLDDVTVEVS P
Highest antigen sequence identity:
- Mouse: 98%
- Rat: 95%
Target Information
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. Plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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