ELK Biotechnology EphA7 rabbit pAb
EphA7 단백질에 특이적인 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 세포막 단일 통과형 단백질 검출에 적합하며, 신경계 발달 및 암 연구에 활용 가능.
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제품명
EphA7 rabbit pAb
제품 개요
EphA7 단백질에 대한 토끼 폴리클로날 항체입니다. Ephrin 수용체 하위 패밀리에 속하는 단백질로, 주로 신경계 발달 및 종양 관련 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EPHA7; EHK3; HEK11; Ephrin type-A receptor 7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human EPHA7 (AA range: 451–500) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 112 kDa |
| Gene ID (Human) | 2045 |
| Human Swiss-Prot No. | Q15375 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors are implicated in mediating developmental events, particularly in the nervous system. Receptors in this subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats. Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand-binding affinity (ephrin-A or ephrin-B). Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, Dec 2013]
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