ELK Biotechnology eIF4G rabbit pAb
인간 eIF4G 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 세포질 내 eIF4F 복합체 구성요소 검출에 유용하며, 고순도 IgG 형태로 -20°C에서 장기 보관 가능합니다.
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ELK Biotechnology eIF4G rabbit pAb
제품 개요
eIF4G rabbit pAb는 인간 eIF4G 단백질을 타깃으로 제작된 토끼 다클론 항체입니다. 이 항체는 단백질 합성 개시 복합체 EIF4F의 주요 구성요소인 eIF4G를 검출하는 데 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | eIF4G rabbit pAb |
| Alternative Names | EIF4G1; EIF4F; EIF4G; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220 |
| Applications | IHC; IF; WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000 IHC: 1:100–1:300 IF: 1:200–1:1000 ELISA: 1:5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human eIF4G (AA range: 1074–1123) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 175 kDa |
| Gene ID (Human) | 1981 |
| Human Swiss-Prot No | Q04637 |
| Cellular Localization | Cytoplasm, Stress granule |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. (RefSeq, Aug 2010)
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